Bol was drafted with the 44th pick of the 2019 NBA draft by the Miami Heat. He was originally mentioned as a top 5-10 pick but slid in the draft until the second round. He was then traded to the Denver Nuggets.
On September 6, 2019, Bol signed a two-way contract with the Nuggets, splitting time with the Windy City Bulls. He had his first double double in the NBA G League on November 20, recording 16 points, 11 rebounds and two blocks in a 115–105 win over the Fort Wayne Mad Ants. On November 24, the Nuggets recalled Bol.
Bol Bol eventually made his NBA debut in the 2020 NBA Bubble on August 1, 2020, recording 5 points and 4 rebounds under 11 minutes of play in a 125–105 loss to the Miami Heat. Furthermore, because he made his debut after the 2019–20 NBA season suspension, Bol will be considered eligible for any rookie honors for the next season.
Bol joined Oregon as a freshman in the 2018–19 season under head coach Dana Altman. Entering the season, he was considered one of the best prospects for the upcoming NBA draft, although analysts described him as a polarizing prospect in the long term. On November 6, 2018, Bol debuted with a double-double of 12 points, 12 rebounds, and 3 blocks in 23 minutes against Portland State. He later recorded a season-high 32 points and 11 rebounds in an 89–84 loss to Texas Southern. After recording 20 points, 9 rebounds, and 4 blocks in a 66–54 win over San Diego on December 12, Bol injured his left foot, which left him out of commission for the rest of the season. He declared for the NBA draft after his freshman season.
Bol was born on November 16, 1999, in Khartoum, Sudan, as the second child of former National Basketball Association (NBA) star Manute Bol and his wife Ajok Kuag. He was named after his late great-grandfather and Dinka chief Bol Chol Bol. In 1998, after an American missile strike during the Second Sudanese Civil War, Manute was accused of being an American spy and was barred by the Sudanese government from fleeing to the United States. In 2001, the family traveled to Cairo, Egypt, where they were stranded for many months due to visa problems, despite having acquired tickets to the United States from American friends.
In the following year, when Bol was two years old, his family moved to Connecticut as designated political refugees. Upon encouragement from his father, he began playing basketball at age four, although he was initially reluctant. Bol eventually began training with his father in the gym. At age seven, he moved to Olathe, Kansas, a city with a large South Sudanese population. As a 6 ft 5 in (1.96 m) seventh grader, Bol featured in a highlight video at an Indianapolis basketball camp that drew attention from CBS Sports and The Washington Post. His first NCAA Division I offer came from New Mexico State, when he was still in the eighth grade.