PHILADELPHIA, Jan. 10 (Ticker) -- Changes in the starting lineup changed the fortunes of the Portland Trail Blazers.

Nick Van Exel set a franchise record with eight 3-pointers and new starters Damon Stoudamire and Joel Przybilla were part of a balanced attack as the Trail Blazers ended a four-game losing streak with a 109-100 victory over the Philadelphia 76ers.

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Coming off Sunday's loss at New York, Portland coach Maurice Cheeks held a team meeting earlier Monday. He decided to start Stoudamire for Derek Anderson at shooting guard and Przybilla for Theo Ratliff at center.

"One of the reasons that I made the change was to try to get a little bit more energy on the floor," said Cheeks, a former 76ers player and assistant who has won his last two visits to Philadelphia. "It wasn't that I was some genius out on the floor making this move. We needed something to jump-start us early and we got it."

The moves seemed to help everyone involved. Stoudamire scored 22 points, making five of Portland's season-high 14 3-pointers; Przybilla was active with a season-high 10 points and eight rebounds; and Anderson stabilized a shallow bench with 11 points.

"The one thing that I have always said is that you put me and Nick in at the same time, sooner or later, it will cause some matchup problems for the other team," Stoudamire said. "When we hit shots like we did tonight, it will always be a tough guard."

While the changes helped, it also helped that Van Exel was his same old self. He scored 28 points as he made 8-of-13 from the arc, breaking the team mark of seven shared by Terry Porter (twice) and Stoudamire.

"The shots fell for me," Van Exel said. "I got a lot of looks and the guys found me."

"They played off each other and gave us the lift we needed," Cheeks said. "When we needed the big shot, it was either Damon or Nick making the shot each time. They found a little continuity playing together and that's what happened tonight."

Anderson scored 11 points in a 20-6 first-half run that pushed Portland's lead to 41-30 with 8:32 left in the second quarter.

The Sixers trailed, 62-51, at halftime and were shot out of the game by Van Exel, who scored 15 points in the third quarter, all on 3-pointers. He made a pair 33 seconds apart to give the Trail Blazers their largest lead at 89-63 with 2:10 to go.

"We needed a couple of buckets just to shake ourselves free," Van Exel said. "Damon came up with a couple and I came with a couple and we finally put them away."

Philadelphia got no closer than the final margin. It played most of the fourth quarter without Allen Iverson, who had 21 points, nine rebounds and nine assists but fell hard on his hip in the second half. The NBA's leading scorer missed Friday's loss at Minnesota with an ankle sprain.

"I fall down all the time," Iverson said. "I didn't hurt it any worse that my ankle and my shoulder. I was fine."

"We were down quite a bit," Sixers coach Jim O' Brien said. "The guys we put in got us back into a reasonable game and I did not want to risk Allen with that kind of deficit."

The Sixers fell to 7-7 at home. They were returning from a 5-3 road trip that included a win at Portland 15 days ago.

"It's a bad feeling, because we played so well on the road," said Iverson, whose streak of games with a steal ended at 50. "Guys tend to come home and then feel like everything is going to be a cakewalk. We found out tonight that's not so."

Rookie Andre Iguodala scored a season-high 22 points for the Sixers. Zach Randolph scored 18 points for the Blazers, who had six players in double figures.