Kobe Bryant scored 30 points and Lamar Odom had 18 points and 10 rebounds in his season debut Friday night to lead the Los Angeles Lakers to a 107-93 victory over the winless Minnesota Timberwolves.

The Lakers were well-balanced. Andrew Bynum and Chris Mihm each had 10 points and 10 rebounds. Derek Fisher had 11 points and nine assists, and Ronny Turiaf scored 11 points. Bryant chipped in with seven assists.

Al Jefferson had 24 points and 15 rebounds for the Timberwolves, who are off to an 0-4 start. Ryan Gomes added 17 points and Sebastian Telfair scored 15.

Los Angeles took control with an 18-3 burst that began with two minutes left in the second quarter and ended with Fisher's 18-foot jumper for a 68-52 lead four minutes into the third.

The Timberwolves got no closer than seven points the rest of the way.

Odom was coming back from shoulder surgery he had last spring.

Bryant, who seems to be looking to pass more this season, made a couple of fine lobs that Turiaf and Bynum had only to tip in. Bryant was on the receiving end of another, a pass just beneath the rim that Bryant, breaking across under the basket, redirected into the hoop with a flick of his left hand.

Point guard Rashad McCants, second in scoring for Minnesota with a 14.7 average, did not play because of a sprained right ankle. He was hurt in the first quarter of Tuesday's 111-103 loss to Orlando.

Bryant had 14 points by halftime and the Lakers led 56-50. After scoring 12 in the first quarter, Bryant took only two shots in the second and scored two points, both from the free throw line.

Gomes finished the first half with 13 points and Jefferson had 12 points and six rebounds.

The Lakers fell behind 20-12 midway through the opening quarter, but Bryant hit a 3 in the final minute for a 30-28 lead at the end of the period.

Gomes had nine points for the Timberwolves in the first quarter.

Notes: Bryant totaled 90 points in the Lakers' final two games against Minnesota last season. ... Los Angeles F-C Kwame Brown missed his second consecutive game because of bursitis in his right heel. ... The Timberwolves won one of four meetings with the Lakers last season, a 117-107 overtime win in Minnesota. ... Odom replaced Luke Walton at small forward in the starting lineup. Odom, whose surgery on his left shoulder was last May, didn't show any fear about going inside and mixing it up against the Timberwolves. He drove through the defense for a layup on his first shot of the game, and battled for a rebound on his next trip down the floor.

Kobe Bryant has put up a combined 90 points in his last two games against the Minnesota Timberwolves. This time, he won't even have 10-time All-Star Kevin Garnett to contend with.

Bryant and the Lakers look to keep the Timberwolves winless when the teams meet for the first time this season Friday night at Staples Center.

As the league's scoring leader each of the past two seasons, Bryant has made a habit of big offensive performances against virtually every opponent. He has, however, saved some of his best games for the Timberwolves.

Bryant scored 40 points in a 117-107 loss at Minnesota on March 6 before putting up 50 in a 109-102 home victory over the Timberwolves 12 days later.

In those games, Bryant and the Lakers had to deal with Garnett - an eight-time All-Defensive team member - who is now gone after an offseason trade to Boston.

Averaging 30.5 points through four games, Bryant is bidding to become the first player to lead the NBA in scoring in three straight seasons since Michael Jordan from 1995-98. He scored 28 on Tuesday, but the Lakers (2-2) were unable to win their third straight game and fell 118-104 to visiting New Orleans.

Ronny Turiaf added 15 points and seven rebounds for Los Angeles, which was without starters Kwame Brown and Lamar Odom in its worst defensive performance of the season.

"I think defensively we have to be a little bit more aggressive," Bryant said. "That's kind of where all our games are gonna be won or lost on our defense on the floor. We've been doing a pretty good job as of lately defensively and tonight we let it get away from us."

Brown, who sat out with bursitis in his right heel, expects to play Friday. Odom has been recuperating from shoulder surgery, but could make his season debut in this game.

Minnesota (0-3) became a very different team following the blockbuster trade of Garnett to the Celtics, and the new players have yet to jell. The Timberwolves are off to their worst start since opening 0-6 in 1994-95, but coach Randy Wittman isn't entirely displeased with his team.

"(Winning is) important. They know it. We know it. That's what this league is all about," he told the Timberwolves' official Web site. "But you know what? It's also about doing things the right way and we've done a lot of things the right way. We are 0-3 and I don't want anyone to be happy with that. I'm not happy with it, but I am happy with what we are doing."

Despite a third straight double-double from Al Jefferson, Minnesota was unable to overcome a 16-point fourth-quarter deficit Tuesday in a 111-103 home loss to Orlando.

Jefferson had 25 points and 10 rebounds for the Timberwolves, who played most of the game without starting point guard Rashad McCants.

McCants - second on the team with 14.7 points per game - sprained his right ankle late in the first quarter and did not return. His status for Friday is uncertain.

The Lakers have won four of the last five meetings against the Timberwolves, and three straight matchups between the teams at Staples Center.